Relatives of People with Type 1 Diabetes:

Can type 1 diabetes be prevented?

You can help answer this question by participating in the NIH TrialNet Pathway to Prevention Research Study For Relatives of People With Type 1 Diabetes. When you participate in the Pathway to Prevention Study, you learn your risk of T1D, but we learn so much more! Your blood sample (less than ½ teaspoon) can be used for many other studies to advance our knowledge of T1D.

Pathway to Prevention screening is the first step for all TrialNet prevention studies. Screening is offered at no cost to eligible individuals to evaluate their personal risk of developing the disease. This unique screening can identify the early stages of type 1 diabetes (T1D) years before any symptoms appear. It also helps researchers learn more about how T1D develops and plan new studies exploring ways to prevent it. Detecting T1D at its earliest stage is critical. A simple blood test is all it takes to learn your risk. 

What is risk screening?

  • A free blood test to detect your risk of T1D years before symptoms appear.

TrialNet screening looks for five auto-antibodies that signal an increased risk for T1D. Two or more autoantibodies signal early stage T1D. There may be other autoantibodies yet to be discovered. Another reason why your participation is so important! 

Who can get screened?

  • People between the age of 2 years 6 months and 45 years with a parent, brother, sister, or child with T1D.
  • People between the age of 2 years 6 months and 20 years with a grandparent, aunt/uncle, cousin, niece/nephew, or half-sibling with T1D.
  • Have not been diagnosed with diabetes. 

Why get screened?

  • Family members of people with T1D are at a 15x greater risk of developing T1D.
  • The ability to screen for risk of developing T1D provides an opportunity to participate in research that aims to prevent disease progression. People who have positive antibodies can participate in very promising diabetes prevention trials that are being done at the Berrie Center under the auspices of NIH TrialNet.
  • Participants receive close monitoring—their risk of being diagnosed in diabetic ketoacidosis (DKA) decreases from 30% to less than 4%.

How to get screened?

Screening is free, quick and easy at the Berrie Center or have the blood test done at a doctor’s office or laboratory close to home, if coming to the Berrie Center is not convenient.

To arrange a TrialNet Pathways to Prevention screening, contact the Berrie Center:

James Pring: 212-851-5489 or via email: jp3735@cumc.columbia.edu